Welcome to the Biotage Sample Preparation Blog

      Dilute & shoot ... yourself in the foot

      How to achieve faster sample prep, cleaner extracts, and instant sensitivity gains

      The revolution of microelution in solid phase extraction

      How to meet demands for detection limits with the right sample prep

      When should I choose SPE instead of SLE?

      Protein precipitation vs. traditional protein crash: what's best?

      How do I Develop a Sample Prep Method?

      Is Sample Prep the only thing to consider for successful analyses?

      How do I come up with a starting point for my SPE method?

      What is Crosstalk and how do I Prevent it from Contaminating my Samples?

      What are the first steps to building a proper method?

      Trying to develop a new method? How do I do a literature search?

      Need good sources of reference for sample prep method development?

      Synthetic Cannabinoids: how to extract them from whole blood?

      Why should I filter my samples instead of doing dilute-and-shoot?

      Methods for a drug class or one large panel - what's the difference

      There and Square Again: A Frit Coverage Tale

      Extracting both acidic and basic analytes in a single SLE procedure

      How to extract and analyze for ever-present contaminants of interest?

      Techniques for disrupting protein binding in sample preparation

      Vacuum or positive pressure for processing samples: what's best?

      Determining the Optimal Sample Size for your Sorbent Bed Mass

      How does my sample prep change between GC/MS and LC/MS/MS?

      How to Monitor and Prevent Sample Carryover during Method Development

      Choosing the best Ion Exchange Mode for Solid Phase Extraction

      When should I choose SLE or SPE for sample cleanup?

      When should I choose weak ion exchange SPE phases?

      When should I choose a mixed-mode SPE?

      Why is pH adjustment important for sample prep methods?

      How to determine recovery and matrix effects for your analytical assay

      What’s the Best Way to do Supported Liquid Extraction?

      How to develop a Supported Liquid Extraction method in 16 easy steps

      In-well hydrolysis plates: What are they and do they really work?

      Urine hydrolysis: how did I choose which enzyme to use?

      What is the Role of LogP in Sample Prep Methods?

      How to choose between SPE and SLE?

      Synthetic Opioids: What are they and how do we analyze them?

      Synthetic Benzodiazepines…..there’s more than just Opioids to test for

      How to Get Organized and Stay in Control with Automated Sample Prep

      How to Automate Sample Prep in the GLP Analytical Lab.

      Automating Sample Prep Boosts Analytical Lab Efficiency

      High Quality Sample Prep is Critical in Analytical Labs