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      Contaminants Everywhere

      July 21, 2021 at 8:15 PM / by Stephen Panos posted in SPE solid phase extraction, EPA Method 537.1, epa method 525.2

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      If you are processing environmental samples then you’ve probably dealt with contamination at some point. If you haven’t, then you should be congratulated for creating the only laboratory on Earth that has ever been completely free of all sources of contamination!

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      Performance vs. Prescriptive Based EPA Methodology

      June 17, 2021 at 2:00 PM / by Deanna Bissonnette posted in SPE solid phase extraction, perscriptive, performance, EPA

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      I am willing to bet there have been a few people reading this that early in their careers have had a moment of “what does that mean” when learning new procedures and or methods. You are about to learn mine. When I was onboarding and learning new standard operating procedures and methods one really stood out and still does to this day. It was when I was first exposed to EPA method 1664B. It stated right in the introduction it is a performance-based method. I thought to myself what does a performance-based method consist of and how do all labs qualify to run it?

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      The Problem of PFAS: Part 2 - Top Regulations

      June 3, 2021 at 3:00 AM / by David Gallagher posted in SPE solid phase extraction, Sample preparation, EPA Method 537.1, per- and polyfluoroalkyl substances, PFAS, Drinking water, EPA Method, water extractions, SPE, perfluorinated compounds, PFOS, extraction, ISOLUTE 101

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      Welcome back! As the title indicates, this is Part 2 of an ongoing series where we discuss what’s going on with PFAS. For those of you who may not have read Part 1, you missed out on a summary of the controversy surrounding this group of compounds and I would recommend going back and taking a quick read through it to make sure that you’re caught up. 

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      What to know when transitioning from EPA method 525.2 to 525.3

      May 20, 2021 at 9:00 AM / by Michael Ebitson posted in SPE solid phase extraction, Drinking water, epa method 525.2, epa method 525.3

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      When learning that you may be transitioning to a newer revision of an EPA method some thoughts may come to mind such as: it took so long to perfect this sample preparation method, or I hope they have some improvements and or greater flexibility allowances in this revision. Well, that is exactly what we will touch upon in this blog post - sample preparation improvements.

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      Why Concentrate Down to 1 mL End Point? Can you go down to 0.5 mL?

      April 29, 2021 at 3:00 PM / by Michael Ebitson posted in SPE solid phase extraction, Sample preparation, tech tips, EPA Method, Drying, application, evaporation systems, lower volume samples

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      When working with regulated environmental methods have you ever asked yourself why are all these extracts concentrated down to one milliliter (mL) final volume? This is true for most soil and aqueous methods. Of course, a few methods will require a more diluted final volume but not many.

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      The Importance of Quality Control on Lab Solvents & SPE Consumables

      April 22, 2021 at 5:00 PM / by Deanna Bissonnette posted in SPE solid phase extraction, epa method 525.2, epa method 525.3, quality control, spe consumables

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      Ever wonder if you need to perform quality control (QC) on solvents and solid phase extraction (SPE) consumables? Well, the answer is yes! You want to make sure that your disks and solvents are good to go before running real-life samples and risk losing that sample. Not only that, but QC samples also help to identify any background in your lab's extraction procedures.

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      Extraction of 1,4-Dioxane from Drinking Water

      March 11, 2021 at 2:30 PM / by Biotage posted in SPE solid phase extraction, epa method 522, UCMR, 1,4 Dioxane

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      1,4-dioxane – sometimes referred to as just dioxane – has gotten a lot of press since the U.S. EPA added it to the third Unregulated Contaminant Monitoring Rule (UCMR 3). It is a relatively common solvent in analytical laboratories; however, it also finds use as a stabilizer for manufacturing items such as shampoo, cosmetics and food additives.

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      In Defense of Methylene Chloride

      December 17, 2020 at 1:45 PM / by Maura Rury posted in SPE solid phase extraction, application

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      If you’re familiar with methylene chloride (which I’m sure you are since it’s one of the most widely used laboratory solvents), you know that it’s developed a reputation for being one of the “bad boys” of the solvent world. The bad press has certainly been earned. It’s been attributed to over 60 deaths in the last 4 decades. It’s also pretty aggressive – exposure to just a few ounces for a few minutes can be enough to cause severe damage or death. And since it’s a colorless liquid, an innocent-looking spill could be a severely harmful hazard.

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      An Alternative To n-Hexane For Doing Oil and Grease Extractions

      December 17, 2020 at 1:45 PM / by Andrew Taylor posted in SPE solid phase extraction, application, oil and grease, n-hexane

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      Volatile. Flammable. Skin irritant. Respiratory irritant. Possibly fatal if swallowed. For those of you processing samples according to EPA Method 1664B, you’ve seen these hazard descriptions before – on the safety data sheet (SDS) for n-hexane. For those of you who aren’t familiar with (or have forgotten about) the hazards related to n-hexane, those are just a few. It also smells unpleasant and could explode if heated. It’s a relatively unpleasant organic solvent to work with and it begs the question:

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      Why Move to Manual or Automated Solid Phase Extraction?

      December 17, 2020 at 1:43 PM / by Deanna Bissonnette posted in SPE solid phase extraction, LLE liquid-liquid extraction, application

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      If you are tired of shaking liquid-liquid extractions (LLE) and want to move onto a technique that is less labor-intensive, solid phase extraction (SPE) may be your answer! There are manual as well as automated options available for solid phase extraction. It may seem like more work for your lab to move to a different technique, but what you gain in time savings may be worth it to you in the end.

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