Do you have issues seeing acceptable recovery of your phenols? I know I do. These compounds can be challenging to recover and quantitate, and are also found just about everywhere! Read on to learn a couple of fun facts about phenols, but first, let’s explain why phenols can be difficult to work with.
Phenolic compounds can be some of the most challenging compounds to extract from the compound lists in EPA Method 8270 and EPA Method 625.1. The recovery of these compounds suffer tremendously compared to some of the other target analytes on the list. So what exactly are phenols and why are they challenging to extract and quantitate?