Smarter Sample Prep for Drug Research Panels

A Complete Guide to Bioanalytical Sample Preparation

You analyze a lot of biological samples. You deliver accurate, reliable data, consistently. You use sophisticated, high-end analytical techniques such as LC-MS/MS or GC-MS. And the pressure is always there to do it faster, with greater sensitivity and, if possible, at lower cost. Sample preparation can be critical for success.

Learn more here on how to choose the right approach for your samples.

Solutions for Urine Drug Panels

Whether you have a few analytes or a very large drug panel to assay, Biotage can help you achieve better results through smarter sample prep options. The hardware and chemistry used for the sample prep is uniquely optimized for your workflow to simplify the process. We understand that labs vary greatly in instrumentation, so our solutions are broadly applicable, whether you are processing manually or on an automated platform. Read More

Trending Application Notes

An In-Well Hydrolysis Solid Phase Extraction Method
Using EVOLUTE® HYDRO CX for 96 Licit and Illicit Drugs
of Abuse from Urine Prior to UPLC-MS/MS

This application note describes the extraction of 96 licit and
illicit drugs of abuse from urine prior to UPLC-MS/MS analysis
using EVOLUTE® HYDRO CX 96-well plates. Read More

Trending Application Notes

Extraction of Tobacco-Specific Nitrosamines (TSNAs) from Urine Using ISOLUTE® SLE+ Prior to UPLC/MS/MS Analysis

This application note describes a method for extracting nitrosamines from urine. The ISOLUTE® SLE+ sample preparation method allows for a fast extraction with sufficient sample clean up, resulting in clean extracts. Read More

White Paper

Current Methodologies for Drugs of Abuse Urine Testing

This white paper examines a number of aspects of sample preparation, and their impact on the success of subsequent LC-MS/MS analysis of broad urine panels. Originally published in 2017, the white paper has now been updated to include details of additional hydrolysis enzymes and optimum hydrolysis conditions.

Highlighted Products

ISOLUTE® SLE+ Supported Liquid Extraction 

ISOLUTE® SLE+ Supported Liquid Extraction plates and columns are designed to provide stress free extraction of analytes from biological fluids, with high analyte recoveries, and clean, protein and phospholipid free extracts. Methods are easy to develop, and automation is simple. Read More

Highlighted Products

EVOLUTE® EXPRESS CX

EVOLUTE® EXPRESS Sample Preparation products provide robust, reliable SPE, giving ultra-pure extracts and high analyte recoveries. Developed specifically for analyte quantification by LC-MS/MS, EVOLUTE sorbents provide a highly effective solution to the problems of ion suppression and matrix effects. Eliminate conditioning and equilibration with EVOLUTE EXPRESS load-wash-elute SPE. Read More

Highlighted Video

ISOLUTE® HYDRO DME+ Dual Mode Extraction Products

The Fast, Affordable Way to Clean up Biological Samples for LC-MS/MS

ISOLUTE® HYDRO DME+ columns and plates provide extremely efficient removal of matrix components and hydrolysis enzyme from urine and other biological fluid samples, using a simple pass through workflow. Read More