Welcome to the Biotage Sample Preparation Blog

      Setting yourself up for Success

      May 27, 2021 at 8:36 AM / by Jeremy Smith posted in LC-MS, GC-MS, SPE, Positive Pressure, High Throughput, Low Volume Extractions, mass spec

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      Developing a new sample prep method should be systematic to ensure ruggedness, and can be done quickly with the right tools. The days of using a vacuum manifold are gone, along with the variability and long extraction times incurred. Today’s options provide an array of positive pressure systems that process a wide range of sample matrices, varying in viscosities.

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      Challenges in developing new laboratory methods...

      May 27, 2021 at 8:05 AM / by Jillian Neifeld, MS posted in LC-MS, GC-MS, SPE, High Throughput, Low Volume Extractions, mass spec

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      So you’ve decided that you need to develop some new methods and one of the biggest challenges is the cost of developing and validating new methods. So, what to do to speed up the process?

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      No one wants to do sample prep if they don’t have to...

      May 27, 2021 at 8:00 AM / by Elena Gairloch posted in LC-MS, GC-MS, SPE, High Throughput, Low Volume Extractions

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      Many Labs today are faced with the challenge of having to do more with existing personnel and space. When looking at developing or modifying a LC/MS or GC/MS assay, one of the most important steps is the sample prep.

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      Microelution plate processing: What pressure is best?

      March 16, 2021 at 3:33 PM / by Charlotte Hayes posted in Troubleshooting and Optimization, Extraction method optimization, Microelution, SPE, positive pressure processing

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      Microelution SPE is a great alternative to conventional SPE methods, enabling the use of lower wash and elution volumes, while maintaining sufficient load volumes, providing concentrated samples, perfect for highly sensitive analysis. Achieving the best, most consistent results means using the right processing conditions, and because all microelution SPE plates are not the same, you might need to adjust your processing conditions when using these plates.

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